All men will develop prostate cancer if they live long enough and lack of vitamin Dmay be the most likely cause. For the first time, Harvard researchers offer a logical explanation for the very high incidence of prostate cancer (3). Prostate cancer is most common in men who eat a high fat, high-saturated fat, high -polyunsaturated fat and high partially hydrogenated fat diet (1), found in meat, chicken, dairy products and extracted vegetable oils. Prostate cancer is also very common in men who eat a high-calcium and low vitamin D diet (2). For example, diary products increase risk and vitamin D supplements reduce risk.

A high-meat and high dairy diet lowers blood levels of the active form of vitamin D [1,25(OH)(2)D]. Meat is loaded with phosphorous, and diary products are loaded with calcium and phosphorus which lower blood levels of the active form of vitamin D called 1,25(OH)(2)D vitamin D. Sulfur-containing amino acids from animal protein make blood acidic which suppresses active vitamin D production. Additionally, high fructose consumption in sugary products lowers blood levels vitamin D (2,3). So the combination of meat, chicken, diary products, calcium supplements and lack of vitamin D combine to increase a man's chances of getting prostate cancer.

1) MM Lee, RT Wang, AW Hsing, FL Gu, T Wang, M Spitzitle. Case-control study of diet and prostate cancer in China. Cancer Causes & Control 9: 6 (DEC 1998):545-552. The data suggest that dietary fat, both saturated and unsaturated, are associated with an increased risk for prostate cancer in a low risk population.

2) JM Chan, E Giovannucci, SO Andersson, J Yuen, HO Adami, A Wolk. Dairy products, calcium, phosphorous, vitamin D, and risk of prostate cancer (Sweden). Cancer Causes & Control 9: 6 (DEC 1998):559-566.

3) E Giovannucci. Dietary influences of 1,25(OH)(2) vitamin D in relation to prostate cancer: A hypothesis. Cancer Causes & Control 9: 6 (DEC 1998):567-582.

Reported 3/29/99; checked 8/9/05

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