Exciting new studies from Umea University in Sweden and UCLA show that planting prostate cancer cells in mice causes prostate cancer, and feeding mice soybeans and whole grain rye prevents the prostate cancers from growing.

Soybeans contain an isoflavone called genistein that has been shown in several studies to inhibit the growth of human prostate cancers in test tubes. Men who eat the most soybeans are least likely to develop prostate cancer. The male hormone, testosterone, stimulates the prostate to grow and uncontrolled growth is cancer. The female hormone, estrogen, may help to dampen the effects of testosterone.

We know that testosterone worsens acne and giving estrogen helps to treat this condition. The plant estrogen, genistein, probably dampens the effects of testosterone. Plant estrogens help to prevent breast cancer because they are so much weaker than human estrogen. Plant estrogen binds to estrogen receptors in breasts to decrease stimulation of human estrogen. Plant estrogen may do the same to prostate cells.

1) A Bylund, JX Zhang, A Bergh, JE Damber, A Widmark, A Johansson, H Adlercreutz, P Aman, MJ Shepherd, G Hallmans. Rye bran and soy protein delay growth and increase apoptosis of human LNCaP prostate adenocarcinoma in nude mice. Prostate, 2000, Vol 42, Iss 4, pp 304-314. Address Bylund A, Umea Univ, Dept Community Med & Rehab, SE-90185 Umea, SWEDEN.

2) WJ Aronson, CN Tymchuk, RM Elashoff, WH McBride, C McLean, HJ Wang, D Heber. Decreased growth of human prostate LNCaP tumors in SCID mice fed a low-fat, soy protein diet with isoflavones. Nutrition and Cancer - an International Journal, 1999, Vol 35, Iss 2, pp 130-136. Address Aronson WJ, Univ Calif Los Angeles, Dept Urol, Sch Med, Box 951738, Los Angeles,CA 90095 USA

Reported 3/28/00; checked 8/9/05

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