NO CURE FOR VENEREAL WARTS
Report #6367 11/19/94
A study in October's Journal of Reproductive Medicine shows that the conventional treatment with laser, anticancer creams and acids can cure visible large venereal warts, but they do not get rid of the small invisible ones in a woman's vagina. (1)
Most warts go away by themselves with time, but some will remain and can eventually cause cancer of the opening to the uterus and penis and possibly the prostate, with older people more likely to have persistent warts.(2) Venereal warts are the most-common venereal disease in the United States today, affecting from 25 to 50% of sexually-active polygamous men and women. They can appear as small bumps on the skin around the genital area, they can form growths the size of a baseball or they can be so small that they can't be seen by the naked eye.
All women who have ever had venereal warts must be followed with PAP smears regularly for the rest of their lives. Before a woman develops cervical cancer, normal cells in the opening to the uterus change slowly to become increasingly more premalignant. A doctor uses a wooden stick to scrape cells from the opening of the cervix and places them on a special slide. Then the cells on the slides are analyzed to see if they look premalignant of malignant. If they do, the doctor usually gives a woman antibiotics to see if the Pap smear will return to normal. If it doesn't, the doctor usually removes or destroys cells lining the opening to the uterus, before they become a cancer.
By Gabe Mirkin, M.D., for CBS Radio News
1) N Husseinzadeh, JG Guoth, DS Jayawardena. Subclinical cervicovaginal human
papillomavirus infections associated with cervical condylomata and dysplasia - Treatment
outcomes. Journal of Reproductive Medicine 39: 10 (OCT 1994):777-780.
2) A Hildesheim, MH Schiffman, PE Gravitt, AG Glass, CE Greer, T Zhang, DR Scott, BB
Rush, P Lawler, ME Sherman, RJ Kurman, MM Manes Journal of Infectious Diseases.
1994(Feb);169(2): 235-240.
3) The presence of HPV DNA is best predicted by the number of new sexual partners in the
last 5 years. Transiently detectable HPV DNA is one possible explanation for this
observation. CK Fairley, SJ Chen, A Ugoni, SN Tabrizi, A Forbes, SM Garland. Human
papillomavirus infection and its relationship to recent and distant sexual partners.
Obstetrics and Gynecology 84: 5 (NOV 1994): 755-7590.
4) Progression depends on histology. Lancet 1994 (August13); 344: 432-435.
5) Human papilloma virus (HPV or human wart viruses types 16 and 18) are associated with
cancer of the cervix. Chlamydia, gonorrhea, herpes, etc are not. The Lancet May 1, 1993.
6) Risk Factors Associated with Cervical Human Papillomavirus Infections - A
Case-Control Study. American Journal of Epidemiology 138: 9 (NOV 1 1993):735-745.
7) The Absence of Vaginal Human Papillomavirus 16 DNA in Women Who Have Not Experienced Sexual Intercourse. Obstetrics and Gynecology 83: 5 Part 1 (MAY 1994):735-737