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High Blood Sugar Linked to Prostate Enlargement, Low Testosterone and Prostate Cancer

Metabolic syndrome and type II diabetes are characterized by high blood sugar, insulin, and triglycerides, low HDL and a fatty liver and obesity. Of 490 male adults, average age 58 years old, 37 percent with lower urinary tract obstruction (LUTS) had metabolic syndrome (Adv Urol, published online Jan 23, 2014). Of those with:
• mild LUTS, 37.4 percent had metabolic syndrome,
• moderate LUTS , 46.5 percent had metabolic syndrome and
• severe LUTS, 54.1 percent had metabolic syndrome.
The patients with metabolic syndrome had much larger prostates than those who did not have that syndrome. Obese men and those with higher levels of the bad LDL cholesterol also had larger prostates.

Low Testosterone and Prostate Cancer Linked to Metabolic Syndrome
Of 1,150 men aged 30 years or older, the lower the testosterone, the more likely a man is to have metabolic syndrome. (Urology, published online October 08, 2013). The researchers defined Metabolic Syndrome as a waist circumference of 85 cm or more plus any two of the following: triglyceride 150 mg/dl or higher, good HDL cholesterol level below 40 mg/dL, taking statins, systolic blood pressure of 130 mm Hg or higher, diastolic blood pressure of 85 mm Hg or higher, taking high blood pressure medications, fasting blood sugar 110 mg/dL or higher, or use of a drug to lower high blood sugar.

Men who had any three of the risk factors for metabolic syndrome are one and a half times more likely to develop prostate cancer than those who do not have metabolic syndrome (European Urology, published online February 24, 2014).

Metabolic Syndrome and Diabetes
Metabolic syndrome means you are on your way to becoming diabetic. Diabetes is a disease in which high blood sugar levels damage every cell in your body. When blood sugar levels rise too high (high blood sugar), the pancreas releases large amounts of insulin (high insulin), which converts sugar to a type of fat called triglycerides (high triglycerides). Then your body uses up its good HDL cholesterol to carry triglycerides from the bloodstream to the liver (low HDL). Next, the extra triglycerides carried to the liver are stored in the liver to form a fatty liver. The triglycerides are also stored in your body to make you fat (overweight). These are the components of both metabolic syndrome and Type II diabetes.

Checked 4/30/17

April 6th, 2014
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About the Author: Gabe Mirkin, MD

Sports medicine doctor, fitness guru and long-time radio host Gabe Mirkin, M.D., brings you news and tips for your healthful lifestyle. A practicing physician for more than 50 years and a radio talk show host for 25 years, Dr. Mirkin is a graduate of Harvard University and Baylor University College of Medicine. He is board-certified in four specialties: Sports Medicine, Allergy and Immunology, Pediatrics and Pediatric Immunology. The Dr. Mirkin Show, his call-in show on fitness and health, was syndicated in more than 120 cities. Read More
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