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Note: Vioxx was removed from the US market in 2004; Bextra in 2005; and Celebrex now includes warnings.
A recent study in the Southern Medical Journal shows that some asthmatics who have had serious reactions to aspirin may be able to take the cox-2 inhibitors such as Celebrex and Vioxx.

People who develop asthma in later life are told never to take aspirin or non-steroidal arthritis medicines because they can cause shock, hives, asthma, itchy eyes and nose, diarrhea and stomach cramps. Your body makes two major types of prostaglandins called Cox-1 and Cox-2. Aspirin blocks both cox-1 that prevents stomach ulcers and kidney damage, and cox-2 that causes swelling and pain. Vioxx and Celebrex are arthritis medicines that block cox-2 that cause pain and swelling, but are less likely to cause stomach ulcers and kidney damage. Doctors now recommend that people with late-onset asthma avoid all aspirin-like drugs, but new evidence suggests that some asthmatics may be able to take Vioxx or Celebrex. Check with your doctor.

Successful Use of Cyclooxygenase-2 Inhibitor in a Patient With Aspirin-Induced Asthma. Fred Marks, Kristopher Harrell, and Rick Fischer. Southern Medical Journal. Vol.94, No.2, February 2001

Reported 3/11/01; checked 8/9/05

June 1st, 2013
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About the Author: Gabe Mirkin, MD

Sports medicine doctor, fitness guru and long-time radio host Gabe Mirkin, M.D., brings you news and tips for your healthful lifestyle. A practicing physician for more than 50 years and a radio talk show host for 25 years, Dr. Mirkin is a graduate of Harvard University and Baylor University College of Medicine. He is board-certified in four specialties: Sports Medicine, Allergy and Immunology, Pediatrics and Pediatric Immunology. The Dr. Mirkin Show, his call-in show on fitness and health, was syndicated in more than 120 cities. Read More
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