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Dementia May Be Preventable

No drug available today can cure dementia or Alzheimer's disease, but studies presented at the Alzheimer’s Association International Conference in Los Angeles found that specific healthful lifestyle changes can reduce dementia risk (JAMA, published online July 14, 2019) and that even if you have high genetic risk for Alzheimer’s disease, a healthful lifestyle can reduce your chances of developing dementia (Neurology, published online July 10, 2019). This is very encouraging news, since just about every lifestyle risk factor for suffering a heart attack is also a risk factor for dementia (Alzheimer's & Dementia, May 12, 2018), and we already have extensive data to show that healthful lifestyle factors help to prevent and treat heart disease.

Dementia means loss of brain function, and your chances of being affected increase with age (Neurology, 2013;80(19):1778-83):
• Three percent of those aged 65-74
• 17 percent of those aged 75-84
• 32 percent of those aged 85 or older
Doctors can predict your risk for developing dementia by ordering an MRI which can show decreased volume of grey matter in the brain (Brain Imaging and Behavior, May 9, 2018). Grey matter is where the brain processes speech, hearing, feelings, seeing, and memory. Having low levels of the good HDL cholesterol increases risk for losing brain tissue and developing dementia 20 years later (Brain Imaging and Behavior, September 26, 2018).

The New Studies
A study from Rush University Medical Center in Chicago (Neurology, published online July 10, 2019) followed 2,765 individuals for 10 years and found that older people can reduce their risk for dementia by 60 percent by:
• actively using the brain every day, by writing, playing chess, doing crossword puzzles and so forth
• eating a healthful diet
• avoiding smoke
• avoiding or severely restricting alcohol
• exercising regularly
Their healthful diet consisted of mostly vegetables, nuts, berries, beans, whole grains, seafood, poultry and olive oil, and avoided red meat and processed meats, butter, cheese, pastries, sweets and fried food. Their exercise program consisted of at least 150 minutes a week of biking, walking, swimming, gardening, yard work or similar activities.

Another study, from Exeter Medical School in England, found that people at high genetic risk for dementia who followed a healthful lifestyle for six years had a 32 percent reduction in developing dementia (JAMA, published online July 14, 2019). Studies presented at the same meeting showed that smoking and excessive drinking increase dementia risk. Other recent studies report that:
• Regular exercisers have much higher brain function in later life and exercising in teens also raises memory scores in later life (Age and Ageing, Mar 1, 2019;48(2):241-246).
• A Long-term diet high in vegetables and fruit in middle and late adulthood was associated with less memory loss in men (Neurology, Jan 1, 2019;92(1):e63-e75).
• Being overweight and carrying extra belly fat is associated with dementia and brain shrinkage (Neurology, Jan 9, 2019).

My Recommendations
You may be able to prevent or at least to delay Alzheimer's disease and other forms of dementia with healthful lifestyle habits, such as:
• exercising regularly
• eating a healthful, plant-based diet
• avoiding alcohol and smoking
• exercising your brain with any activity that requires thinking
• avoiding overweight
• avoiding or controlling high blood pressure, high cholesterol and high blood sugar
For more detail, see Aging and Risk for Dementia
Preventing Dementia

July 21st, 2019
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About the Author: Gabe Mirkin, MD

Sports medicine doctor, fitness guru and long-time radio host Gabe Mirkin, M.D., brings you news and tips for your healthful lifestyle. A practicing physician for more than 50 years and a radio talk show host for 25 years, Dr. Mirkin is a graduate of Harvard University and Baylor University College of Medicine. He is board-certified in four specialties: Sports Medicine, Allergy and Immunology, Pediatrics and Pediatric Immunology. The Dr. Mirkin Show, his call-in show on fitness and health, was syndicated in more than 120 cities. Read More
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